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22 April 2025 : Review article  

A Review of Circulating Tumor DNA (ctDNA) and the Liquid Biopsy in Cancer Diagnosis, Screening, and Monitoring Treatment Response

Dinah V. Parums1DEF*

DOI: 10.12659/MSM.949300

Med Sci Monit 2025; 31:e949300

Table 1 Biofluids used for circulating DNA (ctDNA) analysis (the liquid biopsy) [6].

Plasma and serum from blood
Pleural fluid
Bronchoalveolar lavage (BAL) fluid
Peritoneal fluid
Cerebrospinal fluid (CSF)
Lymphatic fluid
Urine
Breast milk
Saliva
Tears, aqueous and vitreous fluid
Vaginal secretions and uterine lavage fluid
Seminal fluid

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750