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04 April 2017 : Review article  

Uninterrupted Aspirin Therapy and Increased Risk of Bleeding After Colonoscopic Polypectomy: A Meta-Analysis

Guangcheng ChenABCDEF, Chulin HuangABCDEF

DOI: 10.12659/MSRev.903614

Med Sci Rev 2017; 4:1-6


The risk of post-polypectomy bleeding in patients undergoing colonoscopy on uninterrupted aspirin therapy has been a matter of debate for many years. A systematic literature search was performed in PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and Chinese Biomedical Literature Database updated on October 2016 for all qualified publications. The search included keywords for aspirin, endoscopic procedure, bleeding, and clinical trials. The selection was not confined regarding types of design or year of publication. Duplicate articles were removed. For each study, the odds ratio and its 95% confidence interval were calculated to assess the association strength between bleeding after colonoscopic polypectomy and uninterrupted use of aspirin. A total of 5 eligible studies were eventually included. Among these 5 case-control studies, only 1 was prospective, and the other 4 were retrospective. Finally, the analysis shows that uninterrupted using of aspirin increased the risk of post-polypectomy bleeding (OR=1.44, 95% CI=1.06–1.96, P=0.02). Our meta-analysis shows that uninterrupted aspirin therapy probably increases the risk of bleeding after colonoscopic polypectomy.

Keywords: Aspirin, Colonoscopy, Meta-Analysis as Topic, Postoperative Hemorrhage

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01 September 2023 : Editorial  

Editorial: A Rapid Global Increase in COVID-19 is Due to the Emergence of the EG.5 (Eris) Subvariant of Omicron SARS-CoV-2

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.942244

Med Sci Monit 2023; 29:e942244


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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750