Progress in neonatal intensive care is associated with the expanded use of invasive procedures, both diagnostic and therapeutic.In multidisciplinary hospitals neonatal intensive care units are responsible for perioperative care of sick newborns requiring surgical intervention.Such an organizational model allows for comprehensive preparation of the patient for surgery and allows optimizing the neonatal care of sick babies. In 12 months of the year 2002 there were 199 surgical procedures performed.in our patients (neurosurgical –23,cardiosurgical – 26,general surgery –111,eye surgery –34 and ENT surgery –5).In all patients perioperative antibiotic prophylaxis was administered. Selective decontamination of gastrointestinal tract was also used for 7 days in our patients,including oral –non-absorbable drugs (colistin, tobramycin, nystatin).Postoperatively we observed:generalized infections (sepsis),surgical wound infections,meningi- tis and urinary tract infections. Pathogens isolated most frequently were: Eschericha coli,Enterobacter cloacae,Enterococcus faecalis,Staphylococcus aureus,Serratia marcescens, Candida albicans and additionally in patients with prolonged hospital stay –Klebsiella pneumoniae.

Keywords: newborn, Intensive Care, Perioperative Care, infections